If the film is in 3D, titles and graphics must respect the 3D volume of the background and be placed on the Z-axis accordingly. Titles can be embedded in the image with care, as achieved to good effect in the opening title and credits of Life of Pi. Normally, end credits are in 2D, since audiences tend to take their glasses off when the pictures stop. If you embed 3D images in the final credits, audiences may (or may not) put the glasses back on.
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